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. 2021 May 20;297(1):100775. doi: 10.1016/j.jbc.2021.100775

Figure 3.

Figure 3

Glycolytic ECAR modified by sodium pyruvate or lactobionic acid pretreatments (0–10 mM) in Mia Paca-2 and QGP1 cells. Glycolytic ECAR values were normalized to 0 mM of sodium pyruvate or lactobionic acid for (A) Mia Paca-2 and (B) QGP1 cells. C and D, percent changes in normalized treatment-modulated glycolytic ECAR values [% (treated − untreated)] for Mia Paca-2 (C) and QGP1 cells (D). Error bars represent SEM. All experiments were done in quintuplicate (technical replicate); n = 3, independent experiments (biological replicate). ∗∗∗p = 0.0001; ∗∗∗∗p < 0.0001, two-way ANOVA test followed by multiple comparison analyses. ECAR, extracellular acidification rate.