Fig. 7.

PAI intensity as a function of time after in vivo injection of Au nanorod-based contrast agents. Two types of PNPs with LSPR at 1000 nm or 785 nm were specifically functionalized to bind the receptors EGFR or HER2, respectively (see the text for the meaning of the abbreviations). (a) Continuous line: signals from EFGR-functionalized Au nanorods. Dashed line: reference signals from non-functionalized Au nanorods. Laser excitation wavelength 1064 nm. (b) Continuous line: signals from HER2-functionalized Au nanorods. Dashed line: reference signals from non-functionalized Au nanorods. Laser excitation wavelength 800 nm. Reprinted with permission from Ref. [84]. Copyright 2008 Optical Society of America.