Table 3.
Relationship between baseline BMI and incidence of any breast cancer according to treatment received and trial
IBIS-I | IBIS-II | |
---|---|---|
HR (95% CI) | HR (95% CI) | |
Placebo | 1.01 (0.99–1.03) | 1.23 (1.09–1.38) |
Tamoxifen | 1.02 (0. 99–1.04) | |
Anastrozole | 1.14 (0.93–1.39) | |
P-interaction | 0.62 | 0.55 |
Analyses adjusted for age, HRT, current or previous history of smoking, IBIS-I participation (IBIS-II analyses only) and menopausal status (IBIS-I analyses only)
Hazard ratios for continuous estimates are per 5 unit increase in baseline BMI