Table 2.
HER2 GPA scoring data | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
BT-474 | SK-BR-3 | MDA-MB-361 | MDA-MB-175 | MCF-7 | ||||||
HER2 | CEN17 | HER2 | CEN17 | HER2 | CEN17 | HER2 | CEN17 | HER2 | CEN17 | |
Mean signal per cell | 15.73 | 3.53 | 13.70 | 4.95 | 8.45 | 3.10 | 3.20 | 2.90 | 2.13 | 3.98 |
Ratio (HER2/CEN17) | 4.46 | 2.77 | 2.73 | 1.10 | 0.53 |
The HER2 GPA scoring data obtained for the five breast cancer cell lines were manually counted from GPA HER2 images and used to determine the mean signal per cell for the HER2 gene and CEN17 from which the HER2/CEN17 ratio is calculated and displayed as shown in the table