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. 2021 Apr 7;78(11):4867–4891. doi: 10.1007/s00018-021-03821-x

Fig. 5.

Fig. 5

Muscle–vasculature relation in DMD. Symptoms related to the microvasculature of striated muscles are listed in boxes. Molecular mechanisms underlying pathogenesis in the muscle-vasculature relation are described in the text. Abbreviations: neuronal nitric oxide synthase (nNOS), soluble guanylyl cyclase (sGC), cyclic guanosine monophosphate (cGMP), vascular endothelial growth factor (VEGF), hypoxia-inducible factor-1α (HIF-1α)