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Pathological complete response (pCR; ypT0ypN0 or ypTisypN0) rate (primary endpoint): the proportion of patients achieving pCR
| Group | No. of patients achieving pCR | pCR rate, % (90% CIa) | Pb |
|---|---|---|---|
| A1 (n = 23) | 15 | 65 (46–81) | 0.24 |
| A2 (n = 22) | 10 | 45 (27–65) | |
| B1 (n = 27) | 5 | 19 (8–35) | 1.00 |
| B2 (n = 27) | 5 | 19 (8–35) |
aClopper–Pearson exact confidence interval
bFisher’s exact test: group A1 versus group A2 or group B1 versus group B2
