Fig. 7.
Stereotypy slope correlated with day 1 brain dopamine, serotonin, and the sum of dopamine and serotonin. Rats were given ICV propranolol or vehicle pretreatment 20 h prior to 7 daily MAMP sessions; stereotypy response was recorded daily from 30 to 50 min after injection, and IST microdialysis was conducted on days 1 and 7 (experiment 3). The slope of stereotypy time across sessions correlated with day 1 (a) dopamine and (b) serotonin AUC0-75 and with (c) the sum of dopamine and serotonin AUC0-75. Correlations were assessed with pretreatment groups combined (n = 8 propranolol, 7 vehicle). SD, standard deviation
