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. 2021 Jun 25;12:3970. doi: 10.1038/s41467-021-24167-9

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2021

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Fig. 7 — Scenarios for the distribution of Rab-GTPases and their respective effector proteins on a DCV. a Model 1: Rab-effector complexes on DCVs concentrate before and after vesicle docking. b Model 2: A hypothetical model shows a universal distribution of the Rab protein complexes, which diffuse, and concentrate at the docking site. c Model 3: Hypothetical model generated from our work proposes a global distribution of Rab protein complexes before and after docking that promotes efficient capture, docking, and recapture of DCVs at the plasma membrane.