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. 2021 Jun 25;11:13340. doi: 10.1038/s41598-021-92722-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Number of recorded visits per years (by January 2021). Total (cumulative) number of patients included in the GMSR by the end of each year is shown by the black solid line, while the number of patients with actual baseline or follow-up visits during the resp. year is shown by the dashed line. The number of visits per year is show as bars, distinguishing baseline and follow-up visits. GMSR German Multiple Sclerosis registry.