Table 1.
Clinical characteristics of sepsis patients and healthy controls.
| Variable | Sepsis (n = 640) Number (%) |
Control (n = 769) Number (%) | p |
|---|---|---|---|
| Demographics | |||
| Age (years), mean ± SEM | 61.9 ± 0.7 | 60.4 ± 0.6 | 0.092 |
| Gender, male/female, n | 422/218 | 482/287 | 0.204 |
| Sepsis status, n (%) | |||
| Sepsis subtype | 354 (55.3) | N.A | |
| Septic shock | 286 (44.7) | N.A | |
| Source of infection, n (%) | |||
| Respiratory tract infection | 413 (64.5) | N.A | |
| Primary bloodstream infection | 88 (13.8) | N.A | |
| Abdominal infection | 173 (27.0) | N.A | |
| Urinary tract infection | 69 (10.8) | N.A | |
| Catheter-associated infection | 48 (7.5) | N.A | |
| Brain | 47 (7.3) | N.A | |
| trauma | 47 (7.3) | N.A | |
| Others | 48 (7.5) | N.A | |
| Infection types, n (%) | |||
| Gram-positive | 97 (15.2) | N.A | |
| Gram-negative | 335 (52.3) | N.A | |
| Mixed Gram-negative and -positive | 201 (31.4) | N.A | |
| Fungus | 143 (22.3) | N.A | |
| Negative blood culture | 62 (9.7) | N.A | |
| Pathogenic bacteria, n (%) | |||
| Acinetobacter baumannii | 163 (25.5) | N.A | |
| Monilia albican | 59 (9.2) | N.A | |
| Yeast sample sporphyte | 39 (6.1) | N.A | |
| Aspergillus | 25 (3.9) | N.A | |
| Klebsiella pneumoniae | 45 (7.0) | N.A | |
| Pseudomonas aeruginosa | 80 (12.5) | N.A | |
| Staphylococcus aureus | 53 (8.3) | N.A | |
| Escherichia coli | 74 (11.6) | N.A | |
| Others | 111 (17.3) | N.A | |
| SOFA score (mean ± SEM) | 9.1 ± 0.2 | N.A | |
| APACHE II score (mean ± SEM) | 26.8 ± 4.5 | N.A | |
| 28-day mortality, n (%) | 165 (25.8) | N.A | |
N.A not applicable, SOFA Sequential Organ Failure Assessment, APACHE II Acute Physiology and Chronic Health Evaluation II.