Table 3.
Genotype and allele frequencies distribution of the NLRP3 rs10754558 in the different sepsis status.
| rs10754558 | Sepsis subtype n (%) | Septic shock n (%) | p | p* | Odds ratio (95% CI) |
|---|---|---|---|---|---|
| GG | 49 (13.8) | 56 (19.6) | 0.011 | 0.015 | – |
| GC | 166 (46.9) | 148 (51.7) | – | – | – |
| CC | 139 (39.3) | 82 (28.7) | – | – | – |
| GG/GC | 215 (60.7) | 204 (71.3) | 0.005 | 0.010 | 1.608 (1.152, 2.245) |
| GC/CC | 305 (86.2) | 230 (80.4) | 0.051 | 0.051 | 0.660 (0.434, 1.004) |
| G | 264 (37.3) | 260 (45.5) | 0.003 | 0.012 | 1.402 (1.120, 1.754) |
| C | 444 (62.7) | 312 (54.5) | – | – | 1.000 (reference) |
95% CI 95% confidence interval.
*False discovery rate-adjusted p-value for multiple hypotheses testing using the Benjamini–Hochberg method.