Table 4.
Genotype and allele frequencies distribution of the NLRP3 rs10754558 in the 28-day surviving and non-surviving sepsis patients.
| rs10754558 | Survivors n (%) | Non-survivors n (%) | p | p* | Odds ratio (95% CI) |
|---|---|---|---|---|---|
| GG | 72 (15.1) | 33 (20.0) | 0.024 | 0.032 | – |
| GC | 225 (47.4) | 89 (53.9) | – | – | – |
| CC | 178 (37.5) | 43 (26.1) | – | – | – |
| GG/GC | 297 (62.5) | 122 (73.9) | 0.008 | 0.032 | 1.700 (1.146, 2.522) |
| GC/CC | 403 (84.8) | 132 (80.0) | 0.148 | 0.148 | 0.715(0.453, 1.128) |
| G | 369 (38.8) | 155 (47.0) | 0.010 | 0.020 | 1.395 (1.083, 1.795) |
| C | 581 (61.2) | 175 (53.0) | – | – | 1.000 (reference) |
95% CI 95% confidence interval.
*False discovery rate-adjusted p-value for multiple hypotheses testing using the Benjamini–Hochberg method.