Table 4.
Serum levels of biomarkers in the group of complicated silicosis A, B and C.
| Complicated Silicosis A (n = 86) | Complicated silicosis B (n = 42) | Complicated silicosis C (n = 21) | p | |
|---|---|---|---|---|
| IL1B | 7.2 (8.8) | 5.1 (2.3) | 6.2 (3.3) | 0.280 |
| IL2R | 491.8 (315.4) | 406.4 (231.2) | 417.5 (243.7) | 0.225 |
| IL-6 | 9.1 (9.7) | 11.4 (13.7) | 10.0 (5.0) | 0.511 |
| IL-8 | 35.6 (20.4) | 50.2 (41.6) | 84.4 (55.2) | < 0.001** |
| TNF-α | 8.3 (18.4) | 4.7 (2.7) | 4.6 (2.2) | 0.312 |
| TGF-β1 | 19.3 (7.6) | 20.1 (9.1) | 21.3 (6.6) | 0.557 |
| LDH | 385.9 (90.9) | 413.0 (88.1) | 503.6 (126.0) | < 0.001** |
| AAT | 142.5 (38.2) | 159.7 (32.4) | 170.4 (30.6) | 0.002* |
| Ferritin | 554.2 (557.2) | 490.7 (322.7) | 1155.4 (1056.6) | 0.001* |
| CRP | 13.9 (24.4) | 13.2 (16.9) | 19.1 (21.2) | 0.573 |
IL1β Interleukin 1 beta, IL2R interleukin 2 receptor subunit alpha, IL-6 Interleukin 6, IL-8 interleukin 8, TNF-α Tumour necrosis factor alpha, TGF-β1 Transforming growth factor-beta 1, AAT alpha-1 antitrypsin, LDH lactate dehydrogenase, CRP C-reactive protein.
Statistical significance was determined using χ2 test and ANOVA test for qualitative and continuous variables, respectively.
*p < 0.05; **p < 0.001.