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. 2021 Jun 25;7:51. doi: 10.1038/s41531-021-00197-4

Table 2.

Fiber density and cross section values of white matter tracts.

HC TD-PD PIGD-PD P-value Cohen’s d
Mean SD Mean SD Mean SD HC vs. TD-PD vs. PIGD-PD HC vs. TD-PDa HC vs. PIGD-PDa TD-PD vs. PIGD-PDa HC vs. TD-PD HC vs. PIGD-PD TD-PD vs. PIGD-PD
ATR 0.49 0.05 0.52 0.05 0.50 0.06 0.014 0.012 0.26 1.00 −0.61 −0.30 0.28
CST 0.74 0.06 0.81 0.07 0.79 0.10 0.000049 0.000036 0.017 0.97 −1.07 −0.65 0.25
Cingulum 0.61 0.06 0.65 0.08 0.63 0.08 0.089 0.084 0.89 1.00 −0.48 −0.21 0.24
Forceps major 0.69 0.08 0.70 0.08 0.70 0.10 0.84 1.00 1.00 1.00 −0.12 −0.06 0.06
Forceps minor 0.46 0.05 0.48 0.05 0.47 0.05 0.028 0.024 0.91 0.66 −0.55 −0.25 0.31
IFOF 0.58 0.06 0.61 0.06 0.59 0.05 0.31 0.096 1.00 0.77 −0.44 −0.14 0.30
ILF 0.54 0.05 0.57 0.06 0.54 0.05 0.051 0.072 1.00 0.26 −0.46 −0.04 0.42
SLF 0.64 0.06 0.68 0.07 0.66 0.08 0.013 0.012 1.00 0.31 −0.63 −0.23 0.36
UF 0.60 0.06 0.63 0.08 0.62 0.07 0.18 0.24 0.59 1.00 −0.37 −0.26 0.12
Genu of CC 0.65 0.09 0.69 0.08 0.67 0.08 0.10 0.10 0.99 1.00 −0.44 −0.22 0.23
Body of CC 0.74 0.08 0.78 0.08 0.75 0.10 0.13 0.14 1.00 0.70 −0.43 −0.11 0.30
Splenium of CC 0.79 0.11 0.81 0.09 0.78 0.11 0.52 1.00 1.00 0.84 −0.16 0.14 0.33

ATR anterior thalamic radiation, CST corticospinal tract, HC healthy controls, IFOF inferior fronto-occipital fasciculus, ILF inferior longitudinal fasciculus, PIGD-PD patients with postural instability and gait disorder Parkinson’s disease, SD standard deviation, SLF superior longitudinal fasciculus, TD-PD patients with tremor-dominant Parkinson’s disease.

aAnalysis of covariance with Bonferroni-adjusted post hoc tests.