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. 2021 Jun 25;11:13323. doi: 10.1038/s41598-021-92725-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Peptide elongation pathway is downregulated in LUSC when compared to LUAD²⁸. The peptide elongation pathway is the most down-regulated pathway according to Reactome analysis with p-value 9.72E−6 and FDR 0.00157. The boxes partially highlighted in brown indicate the number of genes identified in the analysis that are associated with each box.