Table 5.

Top 10 Upregulated and Downregulated GO Biological Pathways.

Top 10 upregulated pathways			Top 10 downregulated pathways
GO term	Pathway	P-value	GO term	Pathway	P-value
GO:0009888	Tissue development	4.45E−07	GO:0002576	Platelet degranulation	2.86E−04
GO:0045104	Intermediate filament cytoskeleton organization	8.82E−07	GO:1901575	Organic substance catabolic process	8.18E−03
GO:0045103	Intermediate filament-based process	9.95E-−07	GO:0009057	Macromolecule catabolic process	8.29E−03
GO:0007155	Cell adhesion	4.25E−06	GO:0045055	Regulated exocytosis	1.05E−02
GO:0022610	Biological adhesion	4.49E−06	GO:0009056	Catabolic process	1.32E−02
GO:0008544	Epidermis development	4.64E−06	GO:00034613	Cellular protein localization	1.80E−02
GO:0098609	Cell–cell adhesion	5.07E−06	GO:0070727	Cellular macromolecule localization	1.89E−02
GO:0034330	Cell junction organization	9.93E−06	GO:0043129	Surfactant homeostasis	2.36E−02
GO:2001233	Regulation of apoptotic signaling pathway	3.06E−05	GO:0016553	Base conversion or substitution editing	2.65E−02
GO:0061436	Establishment of skin barrier	5.65E−05	GO:0048875	Chemical homeostasis within a tissue	2.94E−02