figs1.

Oxidative stress gene expression in whole blood of COVID-19 patients with different severity. (A) Twenty-six oxidative genes were upregulated in severe COVID-19 vs controls comparison, (B) while twelve genes were upregulated in mild COVID-19 vs controls. Results in (A and B) are presented as fold change of gene expression between cases and controls. (C) The expression of MPO, S100A8, and S100A9 were higher in severe compared to mild COVID-19 samples. Results are presented as fold change of gene expression between cases and controls. All fold changes presented in the figure were significant with a p value<0.05. Unpaired student t-test was used to compare between the independent groups. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001(C). The sample size presented in A-C belonged to EGAS00001004503 dataset and were as following; n=10 controls, n=19 mild COVID-19, and n=20 severe COVID-19