Table 1.
Pro-oxidant gene signatures.
| Gene | Approved name | HGNC ID | Location |
|---|---|---|---|
| ACOX1 | acyl-CoA oxidase 1 | HGNC:119 | 17q25.1 |
| ACOX3 | acyl-CoA oxidase 3, pristanoyl | HGNC:121 | 4p16.1 |
| AOC1 | amine oxidase copper containing 1 | HGNC:80 | 7q36.1 |
| AOC2 | amine oxidase copper containing 2 | HGNC:549 | 17q21.31 |
| AOC3 | amine oxidase copper containing 3 | HGNC:550 | 17q21.31 |
| AOX1 | aldehyde oxidase 1 | HGNC:553 | 2q33.1 |
| CYBA | cytochrome b-245 alpha chain | HGNC:2577 | 16q24.2 |
| CYBB | cytochrome b-245 beta chain | HGNC:2578 | Xp21.1-p11.4 |
| DAO | d-amino acid oxidase | HGNC:2671 | 12q24.11 |
| DDO | d-aspartate oxidase | HGNC:2727 | 6q21 |
| DUOX1 | dual oxidase 1 | HGNC:3062 | 15q21.1 |
| DUOX2 | dual oxidase 2 | HGNC:13,273 | 15q21.1 |
| GFER | growth factor, augmenter of liver regeneration | HGNC:4236 | 16p13.3 |
| HAO1 | hydroxyacid oxidase 1 | HGNC:4809 | 20p12.3 |
| HAO2 | hydroxyacid oxidase 2 | HGNC:4810 | 1p12 |
| IL4I1 | interleukin 4 induced 1 | HGNC:19,094 | 19q13.33 |
| LOX | lysyl oxidase | HGNC:6664 | 5q23.1 |
| MAOA | monoamine oxidase A | HGNC:6833 | Xp11.3 |
| MAOB | monoamine oxidase B | HGNC:6834 | Xp11.3 |
| MPO | myeloperoxidase | HGNC:7218 | 17q22 |
| NCF2 | neutrophil cytosolic factor 2 | HGNC:7661 | 1q25.3 |
| NOS1 | nitric oxide synthase 1 | HGNC:7872 | 12q24.22 |
| NOS2 | nitric oxide synthase 2 | HGNC:7873 | 17q11.2 |
| NOS3 | nitric oxide synthase 3 | HGNC:7876 | 7q36.1 |
| NOX1 | NADPH oxidase 1 | HGNC:7889 | Xq22.1 |
| NOX3 | NADPH oxidase 3 | HGNC:7890 | 6q25.3 |
| NOX4 | NADPH oxidase 4 | HGNC:7891 | 11q14.3 |
| NOX5 | NADPH oxidase 5 | HGNC:14,874 | 15q23 |
| PAOX | polyamine oxidase | HGNC:20,837 | 10q26.3 |
| PCYOX1 | prenylcysteine oxidase 1 | HGNC:20,588 | 2p13.3 |
| PIPOX | pipecolic acid and sarcosine oxidase | HGNC:17,804 | 17q11.2 |
| PNPO | pyridoxamine 5′-phosphate oxidase | HGNC:30,260 | 17q21.32 |
| QSOX1 | quiescin sulfhydryl oxidase 1 | HGNC:9756 | 1q25.2 |
| QSOX2 | quiescin sulfhydryl oxidase 2 | HGNC:30,249 | 9q34.3 |
| SMOX | spermine oxidase | HGNC:15,862 | 20p13 |
| SUOX | sulfite oxidase | HGNC:11,460 | 12q13.2 |