Figure 8.
CEBPB and LYN expression during ATRA-induced granulocytic differentiation. (a) Trace of SRM transitions for native and stable isotope labeled peptide standard VLELTAENER of CEBPB. (b) Profile of CEBPB transcript expression during HL60 differentiation (fold change ≥ 2, p-value ≤ 0.05 at 3 h, 24 h, and 96 h) (c) Protein expression level of CEBPB obtained by SRM (three biological replicates) at 3 h, 24 h, 48 h, 96 h. (d) Trace of SRM transitions for native and standard isotopically-labeled peptide TQPVPESQLLPGQR of LYN. (e) Profile of transcript expression LYN during HL60 differentiation (fold change ≥ 2, p-value ≤ 0.05 at 3 h and 96 h). (f) Protein expression level of LYN obtained by SRM (three biological replicates) at 3 h, 24 h, 48 h, 96 h.