Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Administration AAV-DIO-αSyn to nigra induced bradykinesia in DAT-Cre rats. (A) Timeline of experiment. Animals receiving AAV-DIO-αSyn or AAV-mChery were placed in infrared locomotor activity chambers for 12 h (7 p.m. to 7 a.m.) during the dark cycle. (B) Intranigral administration of AAV-DIO-αSyn significantly reduced HACTV, TOTDIST, MOVNO, MOVTIME, and VACTV, while increased RESTIME. * Significant difference determined by t-test.
