Table 1.
Significant improvement in locomotor behaviors after administration of AAV-NAC32 in rats overexpressing αSyn.
| * Two-Way ANOVA | Posthoc NK Test | ||||
|---|---|---|---|---|---|
| p-Value | F Value | p at 4 wks | p at 8 wks | p at 12 wks | |
| HACTV | <0.001 | 16.415 | 0.163 | 0.032 | 0.004 |
| TOTDIST | 0.002 | 12.18 | 0.259 | 0.059 | 0.009 |
| MOVNO | <0.001 | 20.136 | 0.091 | 0.015 | 0.003 |
| MOVTIME | 0.001 | 14.088 | 0.254 | 0.038 | 0.005 |
| RESTIME | 0.001 | 14.09 | 0.254 | 0.038 | 0.005 |
| VACTV | 0.009 | 8.362 | 0.276 | 0.032 | 0.127 |
* Comparison was made in animals receiving AAV-NAC32 and AAV-mCherry from weeks 4 to 8. p and F values were determined by a two-way ANOVA+NK test. HACTV, horizontal activity; TOTDIST, total distance traveled; MOVNO, movement number; MOVTIME, movement time; RESTIME, rest time; VACTV, vertical activity.