Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 18;93:104973. doi: 10.1016/j.meegid.2021.104973

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Elsevier B.V. All rights reserved.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

PMC Copyright notice

Fig. 1 — Bar diagram illustrating the mutation susceptibility (%) of 26 proteins (See Supplementary Table S1 for functions). (A) Considering the mutation count from individual proteins, the mutation susceptibility (Eq. (2)) falls in the following order: Nsp12 > Spike >N protein > ORF3a > Nsp2 > Nsp13 > Nsp3 > ORF8 > Nsp6 > Nsp5 > Nsp1 > Nsp14 > M protein > Nsp4 > Nsp15 > Nsp16 > Nsp7 > ORF7a > Nsp8 > ORF6 > ORF10 > E protein > Nsp9 > ORF7b > Nsp10 > Nsp11. (B) When the mutation position count is considered, the mutation susceptibility (Eq. (3)) falls in the following order: ORF3a > ORF7a > ORF8 > N protein> ORF10 > ORF6 > ORF7b > Nsp2 > Nsp1 > Nsp9 > Nsp15 > E protein > Nsp13 > Nsp5 > Nsp6 > Nsp3 > Nsp8 > Nsp16 > Spike > Nsp12 > Nsp7 > Nsp11 > Nsp4 > M protein > Nsp14 > Nsp10.