Figure 3.

IgG responses are associated with disease severity

(A–H) IgG-positive rate and signal intensity distribution among three patient groups, i.e., non-severe, severe (survivors), and severe (non-survivors) patients for S1 (A), N protein (B), NSP1 (C), NSP7 (D), NSP8 (E), RdRp (F), ORF3b (G), and ORF9b (H). For positive rate analyses, the error bar is given as the 95% confidential interval. The p values were calculated by a two-sided χ² test. ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001, ^∗∗∗∗p < 0.0001; n.s., not significant. For signal intensity analysis, the middle line is the median value; the upper and lower hinges are the values of the 75% and 25% percentile. The p value was calculated by a two-sided t test.