Figure 5.

Antibody responses against non-structural proteins and accessory proteins decrease rapidly after 20 days of symptom onset

(A) Trends of median signal intensities of IgG at different time points for NSP1, NSP7, and ORF3b among three samples groups, i.e., non-severe, severe (survivors), and severe (non-survivors). Samples were grouped per day, and the points with sample number less than four were excluded.

(B) Trends of positive rate of IgG at different time points for NSP1, NSP7, and ORF3b among three samples groups, i.e., non-severe, severe (survivors), and severe (non-survivors). Samples were grouped per 3 days.

(C–E) NSP7-IgG signal dynamic changes for the patients with four to five samples (C) or more samples (D) or for some representative individuals (E). Each line represents one person.