Figure 2.

Protective effect of SOD3 in junctional damage of Caco-2 cells. (A) RNA was isolated from Caco-2 cells treated or co-cultured with SOD3 or SOD3-carrying MSCs, respectively, and the expression of tight/adherence junction markers (ZO-1, occluding and E-cadherin) was detected by quantitative PCR. (B) Proteins were harvested from cells of equal experimental settings and the expression of ZO-1, occludin, and E-cadherin was determined by western blotting. ## p < 0.01, ### p < 0.001 (CTL vs. P.C), ** p < 0.01, *** p < 0.001 (P.C vs. SOD3, SOD3-MSCs and MSCs), $ p < 0.05, $$ p < 0.01 (SOD3, SOD3-MSCs vs. MSCs). Results are shown as mean ± SD. Results show one representative experiment of at least three independent experiments.