Table 1.
Rate constants of N-acetylcysteine reactions with various compounds under different experimental conditions.
| Reactive Species | Rate Constant (M−1·s−1) | Experimental Conditions | Ref. |
|---|---|---|---|
| •OH | 1.36 × 1010 | pH 7, rt | [37] |
| •NO2 | ≈2.4 × 108a ≈1.0 × 107 b |
pH > pKa, rt pH 7.4, rt |
[38] [39] |
| CO3•− | ≈1.0 × 107 1.8 × 108 |
pH 7, rt pH 12, rt |
[40] |
| HNO | 5 × 105 | pH 7.4, 37 °C | [41] |
| O2•− | 68 ± 6 × 103 |
pH 7, rt pH 7.4, 25 °C |
[37] [42] |
| H2O2 | 0.16 ± 0.01 0.85 ± 0.09 |
pH 7.4, 37 °C pH 7.4, 25 °C |
[37] [43] |
| ONOO− | 415 ± 10 | pH 7.4, 37 °C | [44] |