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. 2021 Jun 18;11(6):571. doi: 10.3390/jpm11060571

Table 2.

Recent progress and status of patient-derived tumor models.

Therapeutic Moiety/Combination Target Cancer Type Animal Type Reference
Erlotinib EGFR Glioblastoma Athymic nude mice [100]
Gefitinib and Enzalutamide Androgen receptor and EGFR non-small cell lung cancer and Prostate cancer Chick chorioallantoic membrane (CAM) [101]
Apatinib, Regorafenib, Cabozantinib, Ramucirumab VEGFR2 Gastric cancers Zebrafish [102]
Ramucirumab Her2, FGFR2, cMet Gastric cancers BALB/c nude mice [103]
Bortezomib CDK4 and MDM2 Liposarcoma Mice [104]
Pembrolizumab PD-1/PD-L1 Soft Tissue Sarcoma NSG mice [105]
Erdafitinib FGFR Metastatic prostate cancer Male mice [106]
β-elemene and cisplatin-coloaded liposomes Codelivery to reverse MDR Lung cancer C57BL/6 mice [107]