ACE2 |
angiotensin-converting enzyme 2 |
ACE2+ |
overexpression of ACE2 |
AKT |
protein kinase B |
ATP |
adenosine triphosphate |
β-CD |
β-cyclodextrin |
3CLpro |
3C-Like protease |
COVID-19 |
coronavirus disease 2019 |
cryo-EM |
cryo-electron microscopy |
EBOV |
Ebola virus |
EC50 |
half-maximal effective concentration |
EGFR |
epidermal growth factor receptor |
EMT |
epithelial-mesenchymal transition |
ERK |
extracellular signal-regulated kinase |
FDA |
US Food and Drug Administration |
GSH |
glutathione |
HA |
hyaluronic acid |
HCoV-229E |
human coronavirus 229E |
HCPNs |
curcumin and cisplatin nanoparticles |
HIV-1 |
human immunodeficiency virus type 1 |
IC50 |
half-maximal inhibitory concentration |
MAPK |
mitogen-activated protein kinase |
Mcl-1 |
myeloid cell leukemia sequence-1 |
MERS-CoV |
Middle East respiratory syndrome coronavirus |
MMPs |
matrix-degrading metalloproteinases |
Mpro |
main protease |
mTOR |
mammalian target of rapamycin |
NSCLC |
non-small cell lung cancer |
PDB |
Protein Data Bank |
PD-L1 |
programmed death ligand-1 |
PI3K |
phosphoinositide 3-kinase |
PLpro |
papain-like protease |
pSARS-CoV-2 |
SARS-CoV-2 pseudovirus |
QFPD |
Qingfei Paidu decoction |
RdRp |
RNA-dependent RNA polymerase |
ROS |
reactive oxygen species |
S protein |
spike protein |
SARS-CoV |
severe acute respiratory syndrome coronavirus |
SARS-CoV-2 |
severe acute respiratory syndrome coronavirus 2 |
SHL |
Shuanghuanglian oral liquid or injection |
SI |
selectivity index |
TMPRSS2 |
transmembrane protease serine 2 |