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. 2021 Jun 18;9(6):689. doi: 10.3390/biomedicines9060689

Table 2.

Registered clinical trials relating to traditional Chinese medicine prescriptions containing baicalein (active ingredient of Huangqin) for treatment of COVID-19 patients (Chinese Clinical Trial Registry, www.chictr.org/cn/ (accessed on 31 January 2021).

Baicalein (The Active Ingredient of Huangqin) Molecular Mechanisms of Baicalein Herbal Formula Containing Huangqin Registration Number Sample Size of the Control Group
graphic file with name biomedicines-09-00689-i031.jpg RdRp inhibitor via noncovalent incorporation [73], potent antagonists against TMPRSS2 [70], improving respiratory function, decreasing IL-1β and TNF-α levels, and inhibiting cell infiltration [71,72]. Qingfei Paidu decoction ChiCTR2000029433 120
ChiCTR2000030883 100
ChiCTR2000032767 782
Xinguan I decoction ChiCTR2000029637 50
Tanreqing capsules ChiCTR2000029813 36
Tanreqing injection ChiCTR2000029432 72
Kegan Liyan oral liquid ChiCTR2000033720 240
ChiCTR2000033745 240
ChiCTR2000031982 240
Shuanghuanglian oral liquid ChiCTR2000033133 30
ChiCTR2000029605 100
Toujie Quwen granule ChiCTR2000031888 150