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. 2021 Jun 16;13(6):2059. doi: 10.3390/nu13062059

Figure 1.

Figure 1

Schematic diagram of the experimental design. All groups were adapted to the environment and to oral gavage during one week before experiment started. Body weight was measured every two weeks. (1) STD: rats receiving standard diet during the whole experiment; (2) CAF: rats receiving standard diet before cafeteria diet intervention; (3) CAF PRE: rats receiving GSPE preventive treatment for 10 days before the cafeteria diet intervention started; (4) CAF MONTHLY: rats receiving a 5-day GSPE treatment simultaneously with the cafeteria diet once per month. Abbreviations: CAF, cafeteria diet; GSPE, grape seed proanthocyanidin extract; BW, Body weight.