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. 2021 Jun 16;22(12):6438. doi: 10.3390/ijms22126438

Table 1.

Summary of the effect of PEMF and PVDF coating on osteogenesis of MC3T3-E1 cells as compared with the control group of PCL-TCP scaffolds.

PCLTCP + PEMF PCLTCP + PVDF PCLTCP + PEMF + PVDF
Cell Metabolic Activity + 0 +
Cell Proliferation ++ 0 ++
Alkaline Phosphatase Activity 0 0 0
Cell Mineralization 0 + +
Osteogenic Gene expression RUNX2 + 0 +
BSP + + +
OC ++ ++ +++
OP + 0 ++

Table legend: 0 = no significant effect; + = greatest effect smaller than twofold enhancement; ++ = greatest effect is between two- to fivefold enhancement; +++ = greatest effect greater than fivefold enhancement.