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The lid of MsuD is important for active site enclosure.A, the active site lid is disordered in the unliganded MsuD structure, which is displayed as a green surface with portions flanking the lid region as ribbon (blue-white). The disordered region is represented as a dashed black line. B, the ternary-MsuD structure contains an ordered lid (blue) and an ordered C terminus from a separate protein molecule (gray). FMN (cyan) and MS− (magenta) are displayed as sticks.
