Figure 2.

Low expression of LSAMP conferred lung tumor aggressiveness. The TCGA cohort showed the relationship between mRNA levels of OPCML (upper panel, (A)), LSAMP (middle panel, (A)), NTM (lower panel, (A)) and nodal metastasis and tumor stages. Furthermore, the CPTAC cohort showed the protein levels, LSAMP, and NTM (left panel, (B)) in both normal and tumor tissues. The correlation between the protein expression levels of LSAMP and NTM and tumor stages (right panel, B). The immunohistochemical staining of LSAMP from six lung cancer patients (C). * p < 0.05; ** p < 0.01; *** p < 0.005; ns, not significant.