Table 3.

Univariate and multivariate binary regression analysis to determine clinicopathological and immunohistochemical predictors of those likely to undergo neoadjuvant treatment.

Parameter	OR	95% CI	P-value	OR	95% CI	P-value
	Univariable			Multivariable
Age <65 years	2.751	1.498–5.054	0.001∗	4.142	1.940–8.845	<0.001∗
Symptomatic	1.426	0.808–2.516	0.221
IDC	0.647	0.368 - 1.138	0.131
Tumour >50 mm	7.573	4.100–13.985	<0.001∗	10.404	5.253–20.604	<0.001∗
Grade 3	0.774	0.507–1.180	0.234
N2/N3	1.111	0.589–2.063	0.739
ER negative	1.374	0.897–2.105	0.144
PgR negative	1.005	0.660–1.531	0.982
HER2 enriched	1.436	0.930–2.217	0.102

OR; odds ratio, 95% CI; 95% confidence interval, IDC; invasive ductal carcinoma, N2; nodal stage 2, ER; estrogen receptor, PgR; progesterone receptor, HER2; human epidermal growth factor receptor-2 molecular subtype.

∗denotes statistical significance.