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Structure of HIV-1 capsid. (A) The structure of the CA monomer showing the N-terminal domain (NTD), the C-terminal domain and the CypA-binding loop (highlighted) (PDB 4XFY) [20]. (B) The structure of pentameric HIV-1 CA (PDB 3P05) [21]. (C) The structure of hexameric HIV-1 CA (PDB 4XFY) [20]. (D) The hexameric and pentameric subunits assemble into a fullerene conical capsid core (PDB 3J3Y). In this model, the core is composed of 186 hexamers and 12 pentamers [22].
