Table 1.

Binding sites of selected compounds targeting HIV-1 capsid.

Compound	Binding Site	Structural Data 1	Structural Data 2
CAP-1 PDB: 2JPR [167]	CA-NTD: At the apex of a 5-helix bundle, in a deep hydrophobic cavity formed by the protuberance of the Phe32 side chain
NYAD-1 PDB: 2L6E [170]	CA-CTD
PF74 PDB: 4XRQ [186]	NTD–CTD interface
GS-6207 PDB: 6VKV [187]	NTD–CTD interface