Figure 5.
Immunoblot analysis of neuroblastoma cell lines after treatment with pevonedistat. p53WT (cell lines CHLA255 and SKNSH), p53MUT cell lines (SKNAS and LAN1), and p53 knockdown cell line (SH-SY5Ysi-p53) were treated with pevonedistat at their IC50 for 48 h and protein expression was assessed for the proteins listed.