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. 2021 Jun 18;12(6):934. doi: 10.3390/genes12060934

Figure 1.

Figure 1

Figure 1

(a) Full pedigree of the original family. Black symbols refer to thrombotic subjects carrying the combined AT-FV Leiden defect (i.e., SERPINC1-F5 mutations). Grey symbols refer to thrombotic subjects in the absence of any identified defect. The asterisk indicates an asymptomatic carrier of a single F5 p.R506Q defect. The triangle symbol indicates aborted fetus. Dashed frame indicates subfamily described in Figure 1b. (b). Extended pedigree of the previous investigated family [2]. This is part of the full pedigree shown in Figure 1a (dashed frame). The different symbols are specified in figure legend (bottom left of the figure). The triangle symbol indicates aborted fetus. Strike-through symbols indicate dead individuals.