Table 2.
Comparisons between polysomnography-derived variables per subgroup. Data are presented as mean ± standard deviation.
| 6MWT, 85% of Predicted | p Values | NC, 40 cm | p Values | Visceral Fat, 12 Score | p Values | Δchest, 5% Differences | p Values | d-ROMs, 320 Carr.U. | p Values | PAT, 2200 U. cor | p Values | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n, < Versus > | n = 25 | n = 12 | n = 11 | n = 26 | n = 12 | n = 25 | n = 13 | n = 24 | n = 14 | n = 23 | n = 7 | n = 30 | ||||||
| AHI, events/h | 53.7 ± 27.4 | 36.3 ± 14.9 | 0.048 | 32.3 ± 13.1 | 54.6 ± 26.4 | 0.012 | 37.7 ± 14.0 | 52.9 ± 28.1 | 0.087 | 59.1 ± 29.9 | 41.9 ± 20.6 | 0.047 | 37.4 ± 23.0 | 54.5 ± 24.8 | 0.044 | 61.6 ± 30.7 | 44.8 ± 23.3 | 0.117 |
| Apnea, events/h | 22.9 ± 21.5 | 6.4 ± 9.7 | 0.016 | 9.2 ± 12.3 | 21.2 ± 21.7 | 0.097 | 12.6 ± 13.9 | 20.0 ± 22.2 | 0.295 | 21.3 ± 26.7 | 15.6 ± 15.4 | 0.416 | 11.9 ± 16.9 | 21.1 ± 21.2 | 0.179 | 32.5 ± 27.2 | 14.1 ± 16.6 | 0.026 |
| Hypopnea, events/h | 28.6 ± 15.2 | 29.8 ± 11.4 | 0.817 | 23.1 ± 8.7 | 31.5 ± 15.1 | 0.096 | 25.2 ± 8.5 | 30.9 ± 15.8 | 0.251 | 33.9 ± 17.4 | 26.4 ± 11.2 | 0.120 | 25.5 ± 15.3 | 31.2 ± 12.9 | 0.235 | 29.0 ± 14.9 | 29.0 ± 14.0 | 0.995 |
| Stage 1, % | 3.4 ± 2.1 | 5.4 ± 6.5 | 0.174 | 2.9 ± 1.5 | 4.5 ± 4.7 | 0.136 | 2.8 ± 1.7 | 4.6 ± 4.7 | 0.217 | 4.2 ± 2.7 | 3.9 ± 4.7 | 0.897 | 3.3 ± 2.5 | 4.5 ± 4.8 | 0.235 | 6.9 ± 8.1 | 3.4 ± 2.1 | 0.032 |
| Stage 2, % | 58.1 ± 12.4 | 45.1 ± 16.4 | 0.011 | 55.9 ± 11.3 | 52.9 ± 16.4 | 0.588 | 58.9 ± 11.2 | 51.4 ± 16.1 | 0.154 | 53.7 ± 15.6 | 53.9 ± 14.9 | 0.967 | 52.9 ± 13.4 | 54.5 ± 16.1 | 0.365 | 47.8 ± 19.0 | 55.3 ± 13.8 | 0.241 |
| Stage 3–4, % | 11.0 ± 6.4 | 11.0 ± 7.1 | 0.991 | 12.6 ± 7.4 | 10.4 ± 6.1 | 0.331 | 13.0 ± 6.9 | 10.1 ± 6.3 | 0.202 | 10.3 ± 6.2 | 11.5 ± 6.8 | 0.603 | 12.2 ± 7.0 | 10.4 ± 6.3 | 0.753 | 5.4 ± 5.7 | 12.4 ± 6.0 | 0.009 |
| REM, % | 9.7 ± 4.5 | 9.8 ± 7.5 | 0.983 | 10.5 ± 4.7 | 9.4 ± 5.9 | 0.574 | 11.4 ± 3.8 | 8.9 ± 6.1 | 0.197 | 9.9 ± 6.9 | 9.6 ± 4.8 | 0.897 | 10.7 ± 5.5 | 9.1 ± 5.5 | 0.420 | 9.3 ± 6.7 | 9.8 ± 5.3 | 0.802 |
| Desaturation Index, % | 55.4 ± 31.2 | 41.8 ± 21.2 | 0.986 | 31.5 ± 13.9 | 59.2 ± 29.6 | 0.006 | 36.5 ± 13.9 | 57.9 ± 31.6 | 0.032 | 67.0 ± 32.8 | 42.3 ± 22.6 | 0.010 | 37.1 ± 24.1 | 59.4 ± 28.5 | 0.398 | 69.2 ± 34.6 | 46.7 ± 26.1 | 0.062 |
| Mininum SaO2, % ‡ | 74.1 ± 14.7 | 78.9 ± 7.7 | 0.294 | 83.3 ± 7.6 | 72.4 ± 13.4 | 0.017 | 82.0 ± 8.7 | 72.6 ± 13.6 | 0.037 | 70.8 ± 15.3 | 78.2 ± 10.9 | 0.097 | 82.1 ± 8.2 | 71.7 ± 13.8 | 0.019 | 70.4 ± 14.6 | 76.9 ± 12.5 | 0.241 |
| Average SaO2, % ‡ | 87.0 ± 6.1 | 88.7 ± 2.4 | 0.382 | 90.3 ± 2.1 | 86.4 ± 5.7 | 0.038 | 89.9 ± 2.3 | 86.4 ± 5.9 | 0.014 | 85.5 ± 7.3 | 88.7 ± 3.4 | 0.082 | ±89.8 | 86.2 ± 6.0 | 0.016 | 85.1 ± 4.4 | 88.1 ± 5.3 | 0.176 |
| Duration SaO2 < 90%, min ‡ | 48.4 ± 58.5 | 25.3 ± 26.4 | 0.203 | 12.9 ± 18.2 | 52.7 ± 56.1 | 0.029 | 18.3 ± 21.2 | 51.8 ± 57.8 | 0.061 | 63.9 ± 68.5 | 28.5 ± 34.5 | 0.043 | 20.0 ± 19.3 | 53.6 ± 60.2 | 0.052 | 62.9 ± 49.2 | 35.8 ± 51.0 | 0.210 |
Abbreviations: 6MWT: 6-min walk test; AHI: Apnea Hypopnea Index; d-ROMs: reactive oxygen metabolites; n: number of patients; NC: neck circumference; PAT: plasma antioxidant capacity; REM: Rapid Eye Movement; Δchest: chest circumference difference between maximal inhalation and exhalation. ‡ Minimum, Average and Duration of SaO2 < 90% are polysomnography derived parameters.