Skip to main content
. 2021 Jun 17;10(6):1523. doi: 10.3390/cells10061523

Figure 1.

Figure 1

Comparison of the transcriptional program of colonic organoids of WKY and SHR. (A) Volcano plot showing differentially expressed genes (DEGs) comparing the colonic organoids of WKY with SHR (FDR-corrected p < 0.05, absolute fold change ≥ 2, purple dots show downregulated genes in SHR, pink dots show upregulated genes in SHR). Gray plots indicate that the genes were not differentially expressed (n = 5 per group). (B) Hallmark pathways significantly enriched in colonic organoids of SHR compared with WKY (Adjusted p < 0.05). NES: normalized enrichment score. (C) Heat map of DEGs in the annotated pathways, FDR-corrected p < 0.05, absolute fold change ≥ 2.