Table 1.
Characteristics of the study population by KIF11 immunoexpression groups.
| Variables | n (%) | KIF11 IS | p-Value | KIF11 PS | p-Value | KIF11 IRS | p-Value | |||
|---|---|---|---|---|---|---|---|---|---|---|
| ↓n = 26 (38.24) | ↑n = 42 (61.76) | ↓n = 58 (85.29) | ↑n = 10 (14.71) | ↓n = 63 (92.65) | ↑n = 5 (7.35) | |||||
| Age (years) | ||||||||||
| ≤ 60 | 29 (42.65) | 12 (41.38) | 17 (58.62) | 0.80 | 22 (75.86) | 7 (24.14) | 0.09 | 25 (86.21) | 4 (13.79) | 0.16 |
| > 60 | 39 (57.35) | 14 (35.90) | 25 (64.10) | 36 (92.31) | 3 (7.69) | 38 (97.44) | 1 (2.56) | |||
| Gender | ||||||||||
| Male | 34 (50.00) | 13 (38.24) | 21 (61.76) | >0.99 | 28 (82.35) | 6 (17.65) | 0.73 | 31 (91.18) | 3 (8.82) | >0.99 |
| Female | 34 (50.00) | 13 (38.24) | 21 (61.76) | 30 (88.24) | 4 (11.76) | 32 (94.12) | 2 (5.88) | |||
| Grading | ||||||||||
| G1 | 5 (7.35) | 1 (20.00) | 4 (80.00) | 0.68 | 5 (100.0) | 0 (0.00) | 0.46 | 5 (100.00) | 0 (0.00) | 0.11 |
| G2 | 55 (80.88) | 22 (40.00) | 33 (60.00) | 47 (85.45) | 8 (14.55) | 52 (94.55) | 3 (5.45) | |||
| G3 | 8 (11.77) | 3 (37.50) | 5 (62.50) | 6 (75.00) | 2 (25.00) | 6 (75.00) | 2 (25.00) | |||
| pT status | ||||||||||
| T1 | 10 (15.87) | 5 (50.00) | 5 (50.00) | 0.47 | 10 (100.0) | 0 (0.00) | 0.37 | 10 (100.0) | 0 (0.00) | 0.60 |
| T2 | 43 (68.25) | 13 (30.23) | 30 (69.77) | 37 (86.05) | 6 (13.95) | 39 (90.70) | 4 (9.30) | |||
| T3-T4 | 10 (15.87) | 4 (40.00) | 6 (60.00) | 8 (80.00) | 2 (20.00) | 9 (90.00) | 1 (10.00) | |||
| pN status | ||||||||||
| N0 | 30 (45.46) | 9 (30.00) | 21 (70.00) | 0.21 | 25 (83.33) | 5 (16.67) | 0.72 | 27 (90.00) | 3 (10.00) | 0.32 |
| N1-N2 | 36 (54.54) | 17 (47.22) | 19 (52.78) | 32 (88.89) | 4 (11.11) | 35 (97.22) | 1 (2.78) | |||
| TNM stage | ||||||||||
| I | 24 (38.71) | 6 (25.00) | 18 (75.00) | 0.20 | 20 (83.33) | 4 (16.67) | 0.29 | 22 (91.67) | 2 (8.33) | 0.54 |
| II | 24 (38.71) | 12 (50.00) | 12 (50.00) | 21 (87.50) | 3 (12.50) | 22 (91.67) | 2 (8.33) | |||
| III-IV | 14 (22.58) | 5 (35.71) | 9 (64.29) | 14 (100.0) | 0 (0.00) | 14 (100.0) | 0 (0.00) | |||
| Location | ||||||||||
| Head | 60 (88.24) | 23 (38.33) | 37 (61.67) | >0.99 | 53 (88.33) | 7 (11.67) | 0.09 | 56 (93.33) | 4 (6.67) | 0.48 |
| Body-tail | 8 (11.76) | 3 (37.50) | 5 (62.50) | 5 (62.50) | 3 (37.50) | 7 (87.50) | 1 (12.50) | |||
| VI | ||||||||||
| Absent | 39 (72.22) | 17 (43.59) | 22 (56.41) | >0.99 | 33 (84.62) | 6 (15.38) | >0.99 | 37 (94.87) | 2 (5.13) | >0.99 |
| Present | 15 (27.78) | 7 (46.67) | 8 (53.33) | 13 (86.67) | 2 (13.33) | 14 (93.33) | 1 (6.67) | |||
| PNI Absent Present |
22 (34.38) |
10 (45.45) |
12 (54.55) |
0.59 |
16 (72.73) |
6 (27.27) |
0.05 |
19 (86.36) |
3 (13.64) |
0.11 |
| 42 (65.62) | 15 (35.71) | 27 (64.29) | 39 (92.86) | 3 (7.14) | 41 (97.62) | 1 (2.38) | ||||
Abbreviations: IS—immunointensity; PS—immunopercentage; IRS—immunoreactive score; VI—vascular invasion; PNI—perineural invasion. Chi-square or Fisher’s exact test.