Table 3.
Univariate Cox proportional hazards models for overall survival of pancreatic ductal adenocarcinoma patients.
| Variable | Univariate Analysis | |||
|---|---|---|---|---|
| HR | 95% CI | p-Value | ||
| Lower | Upper | |||
| KIF11 IRS (low vs. high) | 0.23 | 0.06 | 0.96 | 0.04 |
| KIF11 IS (low vs. high) | 1.49 | 0.82 | 2.71 | 0.19 |
| KIF11 PS (low vs. high) | 0.41 | 0.17 | 0.98 | 0.045 |
| KIF14 IRS (low vs. high) | 0.44 | 0.24 | 0.79 | 0.006 |
| KIF14 IS (low vs. high) | 0.58 | 0.32 | 1.06 | 0.08 |
| KIF14 PS (low vs. high) | 0.70 | 0.39 | 1.26 | 0.24 |
| Age (≤60 vs. ≥60) | 1.14 | 0.63 | 2.07 | 0.67 |
| Gender (female vs. male) | 0.97 | 0.54 | 1.75 | 0.93 |
| Grade (G1 vs. G2-G3) | 2.12 | 0.51 | 8.00 | 0.30 |
| pN (absent vs. present) | 1.27 | 0.70 | 2.32 | 0.44 |
| pT (T1-T2 vs. T3-T4) | 1.08 | 0.48 | 2.45 | 0.85 |
| Stage (I-II vs. III-IV) | 2.05 | 1.02 | 4.13 | 0.04 |
| PNI (absent vs. present) | 1.47 | 0.79 | 2.76 | 0.23 |
| VI (absent vs. present) | 2.41 | 1.17 | 4.98 | 0.02 |
Abbreviations: HR, hazard ratio; CI, confidence interval; IS—immunointensity; PS—immunopercentage; IRS—immunoreactive score; VI—vascular invasion; PNI—perineural invasion. Bold values denote statistically significant p-values (p < 0.05).