Plasma levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in patients that underwent bariatric surgery were reduced compared to retrospectively matched pre-operated patients. (A–E) Characteristics of matched populations: age (B), body mass index (BMI) (C), glycated hemoglobin (A1C) (D), and sex and ethnicity (E). (F,G) Levels of ALT (F) and AST (G) were lower in the matched post-surgery population. (H) The fraction of patients with abnormal ALT levels were reduced in the matched post-surgical population; ns, non-significant, * p < 0.01 by Mann–Whitney U test (C,D,F,G) or χ2 test (H) and Bonferroni correction.