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. 2021 Jun 17;26(12):3708. doi: 10.3390/molecules26123708

Table 4.

Anti-TB activities of 2G0.HCl against single drug-resistant Mtb strains.

Compound M. tuberculosis H37Rv
(µg/mL)
MTB Strain Resistant to
INH
(µg/mL)
RIF
(µg/mL)
ETB
(µg/mL)
STR
(µg/mL)
2G0.HCl 3.12 6.25 6.25 6.25 6.25
RIF 0.04 0.04 >64 0.19 0.04
INH 0.04 >64 0.04 0.04 0.04
ETB 3.12 NT NT >64 0.78
STR 1.56 NT NT 12.5 >64

RIF: Rifampicin, INH: Isoniaid, ETB: Ethambutol, STR: Streptomycin, NT: Not Tested.