Skip to main content
. 2021 Jun 18;22(12):6531. doi: 10.3390/ijms22126531

Figure 4.

Figure 4

Anakinra and SOD2 ameliorates the inflammatory pathology in vivo: (a) C57BL/6 mice were treated with rotenone in the presence or absence of anakinra and evaluated for lung histopathology. (b–d) C57BL/6 mice were infected intranasally with live A. fumigatus conidia and treated with SiSod2 or equivalent doses of nonspecific, scrambled SiRNA in a volume of 20 µl of duplex buffer before evaluation of fungal growth (log10 cfu mean ± SEM) (b), lung histopathology (c) and cytokine quantification (d) at 3 dpi. Scale bar, 500 μm. **, p < 0.01; ***, p < 0.001, one-way ANOVA.