Figure 11.

Bergenin (60 mg/kg) enhances antioxidant levels in transgenic mice. Antioxidant proteins and enzymes were determined in the hippocampal (HC), prefrontal cortex (PFC) and entorhinal cortex (EC) regions of mouse brains. (A–C) Reduced glutathione (%), (D–F) Glutathione-S-transferase (%), (G–I) Superoxide dismutase (%) (J–L) Catalase (%), level in different regions of mouse brains. Results were expressed as mean ± S.D. *** p < 0.001 versus the 5xFAD Tg mice group, ### p < 0.001 versus the wild type.