Table 1.
Number of incident cases and age-standardized incidence rates (ASR, per 100 000) of dengue infection in 1990 and 2019 and their temporal trends from 1990 to 2019
| Characteristics | Number of incident cases (thousands) | Age-standardized incidence rate (ASR, per 100 000) | |||
|---|---|---|---|---|---|
| 1990 (95% UI) | 2019 (95% UI) | Percentage change (%) 1990–2019 | 1990 (95% UI) | 2011 (95% UI) | |
| Global | 30,667.50 (67,065.58,13,221.73) | 56,878.73 (101,350.56,37,083.10) | 85.47 | 557.15 (1212.53,243.32) | 767.93 (1218.01,571.49) |
| Sex | |||||
| Male | 14,731.80 (31,934.34,6357.66) | 27,476.92 (48,266.00,18,119.74) | 86.51 | 532.12 (1151.75,233.13) | 734.71 (1155.38,549.89) |
| Female | 15,935.71 (34,775.93,6663.92) | 29,401.81 (52,970.48,18,134.79) | 84.50 | 584.29 (1273.15,247.75) | 803.03 (1281.19,579.52) |
| Socio-demographic index | |||||
| Low | 3485.36 (9641.61,1531.56) | 6760.17 (17,551.99,2881.81) | 93.96 | 674.40 (312.10,1861.22) | 770.54 (530.43,1760.01) |
| Low–middle | 15,031.69 (42,614.42,4172.32) | 23,105.50 (57,147.17,9835.36) | 53.71 | 1337.13 (383.83,3760.47) | 1450.87 (828.27,3003.90) |
| Middle | 9219.50 (5466.86,18,185.62) | 18,595.32 (14,549.61,34,471.07) | 101.7 | 532.06 (320.61,1036.57) | 771.83 (634.67,1243.41) |
| High–middle | 2479.91 (1399.06,6671.19) | 6974.25 (3471.75,11,042.54) | 181.23 | 214.76 (120.51,579.03) | 471.55 (267.03,807.69) |
| High | 430.65 (347.22,521.72) | 901.83 (598.62,1293.64) | 109.41 | 54.69 (43.12,66.82) | 94.93 (61.35,135.13) |
| GBD region | |||||
| Andean Latin America | 169.32 (102.62,256.08) | 404.89 (328.86,487.37) | 139.12 | 455.98 (299.54,665.71) | 720.41 (527.02,929.64) |
| Australasia | 37.61 (5.34,97.52) | 55.23 (10.39,136.16) | 46.86 | 185.77 (25.62,483.21) | 192.80 (42.69,458.30) |
| Caribbean | 285.58 (189.37,404.24) | 353.50 (203.82,536.92) | 23.78 | 819.65 (560.26,1141.61) | 1040.64 (957.87,1130.42) |
| Central Latin America | 1149.33 (1049.84,1264.99) | 1938.61 (1626.17,2259.68) | 68.67 | 713.32 (633.97,797.16) | 924.05 (660.17,1213.40) |
| Central Sub-Saharan Africa | 335.35 (158.27,547.88) | 682.91 (202.07,1271.86) | 103.64 | 617.81 (313.33,989.16) | 1250.48 (835.01,1654.33) |
| East Asia | 1818.78 (1474.43,2156.15) | 6712.39 (2397.23,12,619.60) | 269.06 | 148.91 (122.43,176.25) | 371.95 (170.59,643.53) |
| Eastern Sub-Saharan Africa | 815.99 (390.26,1281.66) | 1569.52 (456.82,2780.08) | 92.35 | 435.67 (221.90,671.89) | 457.66 (263.88,667.90) |
| High-income Asia Pacific | 30.75 (20.70,46.30) | 62.06 (47.20,83.72) | 101.82 | 17.95 (11.69,27.62) | 35.61 (28.64,47.77) |
| High-income North America | 14.30 (10.52,18.02) | 24.73 (18.15,31.47) | 72.88 | 4.98 (3.56,6.36) | 7.37 (5.80,8.86) |
| North Africa and Middle East | 344.60 (51.39,737.36) | 702.85 (92.99,1496.29) | 103.96 | 100.95 (20.62,209.55) | 128.35 (53.08,224.18) |
| Oceania | 63.20 (51.60,73.96) | 416.48 (100.49,822.91) | 559.04 | 1009.45 (793.94,1198.93) | 1446.87 (785.74,2197.80) |
| South Asia | 18,065.62 (4659.71,46,434.08) | 31,244.96 (12,047.30,76,498.57) | 72.95 | 1663.51 (444.97,4250.09) | 1835.13 (849.71,3924.66) |
| Southeast Asia | 4885.39 (2769.51,12,939.53) | 7702.04 (6995.48,8563.30) | 57.65 | 1036.23 (600.63,2682.51) | 1104.72 (1023.96,1231.69) |
| Southern Latin America | 74.97 (12.84,188.77) | 111.97 (36.12,249.47) | 49.36 | 151.83 (26.41,381.95) | 166.59 (58.32,350.11) |
| Southern Sub-Saharan Africa | 33.32 (17.71,59.82) | 38.87 (9.94,89.90) | 16.68 | 59.70 (33.39,106.06) | 95.92 (62.01,124.83) |
| Tropical Latin America | 1089.86 (730.93,1477.88) | 2228.75 (1974.94,2482.09) | 104.50 | 710.56 (481.73,959.89) | 1574.05 (909.78,2276.80) |
| Western Sub-Saharan Africa | 1453.55 (870.58,2031.92) | 2628.97 (630.11,4745.25) | 80.87 | 769.29 (484.42,1055.63) | 822.19 (586.04,1045.60) |
| Characteristics | Age-standardized incidence rate (ASR, per 100 000) | |||
|---|---|---|---|---|
| 2019 (95% UI) | EAPC (95% CI) 1990–2011 | EAPC (95% CI) 2011–2019 | EAPC (95% CI) 1990–2019 | |
| Global | 740.38 (1323.07,478.25) | 1.70 (1.62,1.78) | − 0.41 (− 0.62, − 0.20) | 1.20 (1.02,1.37) |
| Sex | 0.00 (0.00,0.00) | |||
| Male | 712.21 (1256.92,466.46) | 1.70 (1.62,1.78) | − 0.36 (− 0.57, − 0.14) | 1.21 (1.04,1.38) |
| Female | 769.95 (1392.94,469.04) | 1.70 (1.62,1.77) | − 0.47 (− 0.68, − 0.26) | 1.18 (1.00,1.36) |
| Socio-demographic index | ||||
| Low | 619.51 (283.41,1614.60) | 0.96 (0.80,1.12) | − 2.78 (− 3.48, − 2.07) | 0.07 (− 0.24,0.38) |
| Low–middle | 1317.83 (554.94,3275.40) | 0.57 (0.50,0.65) | − 1.20 (− 1.24, − 1.16) | 0.18 (0.04,0.32) |
| Middle | 787.68 (616.02,1474.61) | 1.92 (1.73,2.11) | 0.26 (0.07,0.45) | 1.60 (1.45,1.75) |
| High–middle | 522.75 (261.31,859.96) | 3.96 (3.80,4.12) | 1.70 (0.98,2.42) | 3.16 (2.89,3.43) |
| High | 91.79 (61.91,131.49) | 2.98 (2.85,3.10) | 0.08 (− 0.84,1.01) | 2.08 (1.79,2.38) |
| GBD region | ||||
| Andean Latin America | 632.56 (518.08,754.08) | 2.36 (2.19,2.54) | − 0.68 (− 2.47,1.15) | 1.77 (1.50,2.05) |
| Australasia | 188.65 (34.24,466.29) | 0.07 (− 0.05,0.20) | − 0.20 (− 0.40,0.01) | 0.17 (0.09,0.25) |
| Caribbean | 747.08 (427.62,1140.19) | 1.29 (0.87,1.71) | − 4.62 (− 5.43, − 3.80) | − 0.13 (− 0.67,0.40) |
| Central Latin America | 771.16 (651.56,892.79) | 0.61 (0.00,1.23) | − 2.73 (− 3.59, − 1.87) | 0.63 (0.25,1.01) |
| Central Sub-Saharan Africa | 539.27 (197.31,961.59) | 3.81 (2.85,4.77) | − 10.20 (− 14.07, − 6.16) | 0.68 (− 0.50,1.88) |
| East Asia | 494.33 (173.26,942.48) | 5.00 (4.71,5.30) | 4.84 (2.70,7.03) | 4.57 (4.31,4.82) |
| Eastern Sub-Saharan Africa | 382.19 (121.33,666.80) | 0.68 (0.45,0.92) | − 2.12 (− 3.30, − 0.93) | − 0.40 (− 0.77, − 0.04) |
| High-income Asia Pacific | 36.75 (27.11,50.80) | 3.69 (3.30,4.08) | − 0.85 (− 4.51,2.95) | 3.43 (2.99,3.88) |
| High-income North America | 6.44 (4.61,8.32) | 1.31 (0.32,2.30) | − 2.61 (− 6.52,1.47) | 2.35 (1.57,3.13) |
| North Africa and Middle East | 115.37 (17.71,242.93) | 1.22 (1.09,1.35) | − 1.50 (− 2.11, − 0.89) | 0.66 (0.45,0.87) |
| Oceania | 3173.48 (762.33,6161.18) | 0.76 (− 0.64,2.18) | 11.01 (8.79,13.27) | 2.21 (1.25,3.17) |
| South Asia | 1740.79 (660.93,4287.12) | 0.54 (0.51,0.57) | − 0.61 (− 0.72, − 0.51) | 0.25 (0.15,0.35) |
| Southeast Asia | 1153.57 (1049.49,1281.59) | 0.55 (0.23,0.88) | 0.38 (0.13,0.62) | 0.62 (0.45,0.80) |
| Southern Latin America | 167.41 (51.67,376.20) | 0.46 (0.36,0.56) | − 0.13 (− 1.40,1.15) | 0.65 (0.51,0.78) |
| Southern Sub-Saharan Africa | 48.63 (13.05,111.58) | 2.31 (1.45,3.18) | − 8.25 (− 11.78, − 4.57) | 0.03 (− 0.87,0.95) |
| Tropical Latin America | 990.10 (891.27,1089.11) | 4.10 (3.25,4.96) | − 6.80 (− 8.57, − 5.00) | 1.30 (0.26,2.36) |
| Western Sub-Saharan Africa | 606.75 (201.38,1033.46) | 0.41 (0.28,0.53) | − 3.95 (− 4.27, − 3.62) | − 0.45 (− 0.77, − 0.13) |
EAPC estimated annual percentage change, CIs confidence intervals, UIs uncertainty intervals