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. 2021 Jun 26;21:194. doi: 10.1186/s12866-021-02241-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — The positive reaction rates of epitope peptide S21P2, S14P5, P82 and P104 in convalescent sera of COVID-19 patients. Each convalescent serum sample of COVID-19 patients was tested with each epitope peptide by indirect ELISA. a The positive reaction rates of peptides S21P2, S14P5, P82 and P104 in total COVID-19 patients and asymptomatic infections. b Analyses of the positive reaction rates of different peptide combinations. S14P5, S14P5 + S21P2 and S14P5 + S21P2 + P104 were the best combinations with the highest overall positive reaction rate in peptide combinations respectively contained the single, two or the three epitope peptides. As long as the serum sample was positive for any one of the epitope peptides in combination, the sample was considered to be positive for the epitope peptide combination. c The positive reaction rates in different clinical types detected by different peptide combinations