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. 2021 Jun 16;13(12):3021. doi: 10.3390/cancers13123021

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Cytologic diagnosis of NLPHL. (A,B) Wright–Giemsa-stained touch preparations show LP cells in a background of small lymphoid cells and occasional inflammatory cells. (C) H&E section of a core needle biopsy does not readily reveal a nodular architecture. (D) A CD21 stain highlights the FDC meshworks and confirms the presence of nodules. (E) Bright OCT2 staining and (F) prominent PD1-positive rings lend support for the diagnosis of NLPHL. [Original magnifications: A,B ×600; C,D ×40; E,F ×150].