Table 2.

Docking scores (minimal, kcal/mol) of 1 and 10 from their binding to FIH-1, NF-κB, HDACs, IAPs, and PI3K.

Compd./Protein	1	10	Compd./Protein	1	10	Compd./Protein	1	10
FIH-1	−10.6	−9.2	HDAC8	−6.1	−8.3	XIAPBIR1	−6.0	−5.2
NF-κB (p50)	−9.2	−7.7	HDAC6	−7.0	−8.8	cIAP1BIR1	−5.8	−6.2
NF-κB (p52)	−8.5	−6.7	HDAC4	−5.3	−7.6	cIAP1BIR3	−5.7	−5.8
NF-κB (p65)	−8.8	−7.1	ML-IAP	−6.5	−6.3	XIAPBIR2	−6.1	−5.9
HDAC7	−6.9	−7.9	cIAP2BIR1	−5.9	−5.4	XIAPBIR3	−6.6	−5.2
HDAC1	−5.6	−8.3	cIAP2BIR3	−6.9	−6.1	PI3K	−6.4	−7.2